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Imaging the fate of histone Cse4 reveals de novo replacement in S phase and subsequent stable residence at centromeres
The budding yeast centromere contains Cse4, a specialized histone H3 variant. Fluorescence pulse-chase analysis of an internally tagged Cse4 reveals that it is replaced with newly synthesized molecules in S phase, remaining stably associated with centromeres thereafter. In contrast, C-terminally-tag...
Autores principales: | Wisniewski, Jan, Hajj, Bassam, Chen, Jiji, Mizuguchi, Gaku, Xiao, Hua, Wei, Debbie, Dahan, Maxime, Wu, Carl |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067749/ https://www.ncbi.nlm.nih.gov/pubmed/24844245 http://dx.doi.org/10.7554/eLife.02203 |
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