Cargando…

The prevalence of type 2 diabetes mellitus among older people in Africa: a systematic review study protocol

INTRODUCTION: The number of people with diabetes in Africa is projected to increase substantially in the next two decades, due to factors including rapid urbanisation, adoption of unhealthy diets and exercise patterns and the ageing of the population. There are currently uncertainties regarding the...

Descripción completa

Detalles Bibliográficos
Autores principales: Werfalli, Mahmoud, Musekiwa, Alfred, Engel, Mark E, Ross, Ian, Kengne, Andre P, Levitt, Naomi S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067824/
https://www.ncbi.nlm.nih.gov/pubmed/24939807
http://dx.doi.org/10.1136/bmjopen-2013-004747
_version_ 1782322343049166848
author Werfalli, Mahmoud
Musekiwa, Alfred
Engel, Mark E
Ross, Ian
Kengne, Andre P
Levitt, Naomi S
author_facet Werfalli, Mahmoud
Musekiwa, Alfred
Engel, Mark E
Ross, Ian
Kengne, Andre P
Levitt, Naomi S
author_sort Werfalli, Mahmoud
collection PubMed
description INTRODUCTION: The number of people with diabetes in Africa is projected to increase substantially in the next two decades, due to factors including rapid urbanisation, adoption of unhealthy diets and exercise patterns and the ageing of the population. There are currently uncertainties regarding the incidence, prevalence and management patterns of diabetes in older people across the diversity of African countries. We wish to perform a systematic review to determine the prevalence of type 2 diabetes in Africa in the older individual, over the age of 55 years, reported in studies from 2000 to 2013. METHODS AND ANALYSES: A comprehensive literature search among a number of databases will be undertaken, using an African search filter to identify diabetes prevalence studies that were published from 2000 to 2013. Full copies of articles identified by the search, and considered to meet the inclusion criteria, will be obtained for data extraction and synthesis. Statistical analysis of the primary measures, fasting plasma glucose (FPG) and oral glucose tolerance test will include two steps: (1) identification of data sources and documenting estimates and (2) application of the random-effects meta-analysis model to aggregate prevalence estimates and account for between study variability in calculating the overall pooled estimates and 95% CI for diabetes prevalence. Heterogeneity will be evaluated using the I(2) statistic to determine the extent of variation in effect estimates that is due to heterogeneity rather than chance. This systematic review will be reported according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA). ETHICS AND DISSEMINATION: Ethics is not required for this study, given that this is a protocol for a systematic review, which utilises published data. The findings of this study will be widely disseminated through peer-reviewed publications and conference presentations.
format Online
Article
Text
id pubmed-4067824
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher BMJ Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-40678242014-06-25 The prevalence of type 2 diabetes mellitus among older people in Africa: a systematic review study protocol Werfalli, Mahmoud Musekiwa, Alfred Engel, Mark E Ross, Ian Kengne, Andre P Levitt, Naomi S BMJ Open Diabetes and Endocrinology INTRODUCTION: The number of people with diabetes in Africa is projected to increase substantially in the next two decades, due to factors including rapid urbanisation, adoption of unhealthy diets and exercise patterns and the ageing of the population. There are currently uncertainties regarding the incidence, prevalence and management patterns of diabetes in older people across the diversity of African countries. We wish to perform a systematic review to determine the prevalence of type 2 diabetes in Africa in the older individual, over the age of 55 years, reported in studies from 2000 to 2013. METHODS AND ANALYSES: A comprehensive literature search among a number of databases will be undertaken, using an African search filter to identify diabetes prevalence studies that were published from 2000 to 2013. Full copies of articles identified by the search, and considered to meet the inclusion criteria, will be obtained for data extraction and synthesis. Statistical analysis of the primary measures, fasting plasma glucose (FPG) and oral glucose tolerance test will include two steps: (1) identification of data sources and documenting estimates and (2) application of the random-effects meta-analysis model to aggregate prevalence estimates and account for between study variability in calculating the overall pooled estimates and 95% CI for diabetes prevalence. Heterogeneity will be evaluated using the I(2) statistic to determine the extent of variation in effect estimates that is due to heterogeneity rather than chance. This systematic review will be reported according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA). ETHICS AND DISSEMINATION: Ethics is not required for this study, given that this is a protocol for a systematic review, which utilises published data. The findings of this study will be widely disseminated through peer-reviewed publications and conference presentations. BMJ Publishing Group 2014-06-17 /pmc/articles/PMC4067824/ /pubmed/24939807 http://dx.doi.org/10.1136/bmjopen-2013-004747 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 3.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Diabetes and Endocrinology
Werfalli, Mahmoud
Musekiwa, Alfred
Engel, Mark E
Ross, Ian
Kengne, Andre P
Levitt, Naomi S
The prevalence of type 2 diabetes mellitus among older people in Africa: a systematic review study protocol
title The prevalence of type 2 diabetes mellitus among older people in Africa: a systematic review study protocol
title_full The prevalence of type 2 diabetes mellitus among older people in Africa: a systematic review study protocol
title_fullStr The prevalence of type 2 diabetes mellitus among older people in Africa: a systematic review study protocol
title_full_unstemmed The prevalence of type 2 diabetes mellitus among older people in Africa: a systematic review study protocol
title_short The prevalence of type 2 diabetes mellitus among older people in Africa: a systematic review study protocol
title_sort prevalence of type 2 diabetes mellitus among older people in africa: a systematic review study protocol
topic Diabetes and Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067824/
https://www.ncbi.nlm.nih.gov/pubmed/24939807
http://dx.doi.org/10.1136/bmjopen-2013-004747
work_keys_str_mv AT werfallimahmoud theprevalenceoftype2diabetesmellitusamongolderpeopleinafricaasystematicreviewstudyprotocol
AT musekiwaalfred theprevalenceoftype2diabetesmellitusamongolderpeopleinafricaasystematicreviewstudyprotocol
AT engelmarke theprevalenceoftype2diabetesmellitusamongolderpeopleinafricaasystematicreviewstudyprotocol
AT rossian theprevalenceoftype2diabetesmellitusamongolderpeopleinafricaasystematicreviewstudyprotocol
AT kengneandrep theprevalenceoftype2diabetesmellitusamongolderpeopleinafricaasystematicreviewstudyprotocol
AT levittnaomis theprevalenceoftype2diabetesmellitusamongolderpeopleinafricaasystematicreviewstudyprotocol
AT werfallimahmoud prevalenceoftype2diabetesmellitusamongolderpeopleinafricaasystematicreviewstudyprotocol
AT musekiwaalfred prevalenceoftype2diabetesmellitusamongolderpeopleinafricaasystematicreviewstudyprotocol
AT engelmarke prevalenceoftype2diabetesmellitusamongolderpeopleinafricaasystematicreviewstudyprotocol
AT rossian prevalenceoftype2diabetesmellitusamongolderpeopleinafricaasystematicreviewstudyprotocol
AT kengneandrep prevalenceoftype2diabetesmellitusamongolderpeopleinafricaasystematicreviewstudyprotocol
AT levittnaomis prevalenceoftype2diabetesmellitusamongolderpeopleinafricaasystematicreviewstudyprotocol