Detection of Hodgkin Transformation in a Case of Chronic Lymphocytic Leukemia by PET/CT

Richter’s transformation (RT) represents the development of high grade lymphoma, most commonly diffuse large B-cell lymphoma, in patients with chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL/SLL). CLL/SLL may convert also to Hodgkin’s lymphoma, the so-called Hodgkin’s variant of Rich...

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Detalles Bibliográficos
Autores principales: Yılmaz, Sabire, Özhan, Meftune, Asa, Sertaç, Sağer, M. Sait, Biricik, Fatih Selçuk, Halaç, Metin, Sönmezoğlu, Kerim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067880/
https://www.ncbi.nlm.nih.gov/pubmed/24963449
http://dx.doi.org/10.4274/mirt.362
Descripción
Sumario:Richter’s transformation (RT) represents the development of high grade lymphoma, most commonly diffuse large B-cell lymphoma, in patients with chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL/SLL). CLL/SLL may convert also to Hodgkin’s lymphoma, the so-called Hodgkin’s variant of Richter transformation. Histopathological proof is needed to confirm a definitive diagnosis. Patients with RT generally have a poor prognosis, with prompt recognition optimise clinical management. Whole-body PET scan with 18F-FDG can be used for detection of RT of CLL/SLL. We describe the case of 64-year-old woman with CLL/SLL who developed Hodgkin lymphoma detected with PET/CT.

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