A Case of Primary Subglottic Malignant Melanoma with a Successful Surgical Treatment

Primary subglottic malignant melanoma is a very rare and underdiagnosed neoplasm. We are reporting a case of primary malignant melanoma of subglottic mucosa in a 78-year-old woman who presented to our hospital with shortness of breath and hoarseness of voice. Laryngoscopy and excisional biopsy along...

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Autores principales: Ahmad, Shahzad, Abdelghany, Mahmoud, Goldblatt, Curtis, Stark, Owen, Masciotra, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068050/
https://www.ncbi.nlm.nih.gov/pubmed/24995141
http://dx.doi.org/10.1155/2014/968926
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author Ahmad, Shahzad
Abdelghany, Mahmoud
Goldblatt, Curtis
Stark, Owen
Masciotra, Nicholas
author_facet Ahmad, Shahzad
Abdelghany, Mahmoud
Goldblatt, Curtis
Stark, Owen
Masciotra, Nicholas
author_sort Ahmad, Shahzad
collection PubMed
description Primary subglottic malignant melanoma is a very rare and underdiagnosed neoplasm. We are reporting a case of primary malignant melanoma of subglottic mucosa in a 78-year-old woman who presented to our hospital with shortness of breath and hoarseness of voice. Laryngoscopy and excisional biopsy along with immunoreactivity to S-100 and human melanoma black-45 (HMB-45) confirmed the diagnosis. The patient was treated with laryngectomy followed by radiotherapy. Five years following surgical treatment, she continues to be asymptomatic. To our knowledge, there is only one reported case of primary malignant melanoma of subglottic mucosa in the medical literatures.
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spelling pubmed-40680502014-07-03 A Case of Primary Subglottic Malignant Melanoma with a Successful Surgical Treatment Ahmad, Shahzad Abdelghany, Mahmoud Goldblatt, Curtis Stark, Owen Masciotra, Nicholas Case Rep Oncol Med Case Report Primary subglottic malignant melanoma is a very rare and underdiagnosed neoplasm. We are reporting a case of primary malignant melanoma of subglottic mucosa in a 78-year-old woman who presented to our hospital with shortness of breath and hoarseness of voice. Laryngoscopy and excisional biopsy along with immunoreactivity to S-100 and human melanoma black-45 (HMB-45) confirmed the diagnosis. The patient was treated with laryngectomy followed by radiotherapy. Five years following surgical treatment, she continues to be asymptomatic. To our knowledge, there is only one reported case of primary malignant melanoma of subglottic mucosa in the medical literatures. Hindawi Publishing Corporation 2014 2014-06-08 /pmc/articles/PMC4068050/ /pubmed/24995141 http://dx.doi.org/10.1155/2014/968926 Text en Copyright © 2014 Shahzad Ahmad et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ahmad, Shahzad
Abdelghany, Mahmoud
Goldblatt, Curtis
Stark, Owen
Masciotra, Nicholas
A Case of Primary Subglottic Malignant Melanoma with a Successful Surgical Treatment
title A Case of Primary Subglottic Malignant Melanoma with a Successful Surgical Treatment
title_full A Case of Primary Subglottic Malignant Melanoma with a Successful Surgical Treatment
title_fullStr A Case of Primary Subglottic Malignant Melanoma with a Successful Surgical Treatment
title_full_unstemmed A Case of Primary Subglottic Malignant Melanoma with a Successful Surgical Treatment
title_short A Case of Primary Subglottic Malignant Melanoma with a Successful Surgical Treatment
title_sort case of primary subglottic malignant melanoma with a successful surgical treatment
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068050/
https://www.ncbi.nlm.nih.gov/pubmed/24995141
http://dx.doi.org/10.1155/2014/968926
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