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Systems biology approaches to understanding Epithelial Mesenchymal Transition (EMT) in mucosal remodeling and signaling in asthma

A pathological hallmark of asthma is chronic injury and repair, producing dysfunction of the epithelial barrier function. In this setting, increased oxidative stress, growth factor- and cytokine stimulation, together with extracellular matrix contact produces transcriptional reprogramming of the epi...

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Detalles Bibliográficos
Autores principales:	Ijaz, Talha, Pazdrak, Konrad, Kalita, Mridul, Konig, Rolf, Choudhary, Sanjeev, Tian, Bing, Boldogh, Istvan, Brasier, Allan R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	World Allergy Organization 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068075/ https://www.ncbi.nlm.nih.gov/pubmed/24982697 http://dx.doi.org/10.1186/1939-4551-7-13

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