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SIVA1 directs the E3 ubiquitin ligase RAD18 for PCNA monoubiquitination

Translesion DNA synthesis (TLS) is a universal DNA damage tolerance mechanism conserved from yeast to mammals. A key event in the regulation of TLS is the monoubiquitination of proliferating cell nuclear antigen (PCNA). Extensive evidence indicates that the RAD6–RAD18 ubiquitin-conjugating/ligase co...

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Detalles Bibliográficos
Autores principales:	Han, Jinhua, Liu, Ting, Huen, Michael S.Y., Hu, Lin, Chen, Zhiqiu, Huang, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2014
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068132/ https://www.ncbi.nlm.nih.gov/pubmed/24958773 http://dx.doi.org/10.1083/jcb.201311007

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