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SLK-dependent activation of ERMs controls LGN–NuMA localization and spindle orientation

Mitotic spindle orientation relies on a complex dialog between the spindle microtubules and the cell cortex, in which F-actin has been recently implicated. Here, we report that the membrane–actin linkers ezrin/radixin/moesin (ERMs) are strongly and directly activated by the Ste20-like kinase at mito...

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Detalles Bibliográficos
Autores principales: Machicoane, Mickael, de Frutos, Cristina A., Fink, Jenny, Rocancourt, Murielle, Lombardi, Yannis, Garel, Sonia, Piel, Matthieu, Echard, Arnaud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068135/
https://www.ncbi.nlm.nih.gov/pubmed/24958772
http://dx.doi.org/10.1083/jcb.201401049

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