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A single domain of the ZP2 zona pellucida protein mediates gamete recognition in mice and humans

The extracellular zona pellucida surrounds ovulated eggs and mediates gamete recognition that is essential for mammalian fertilization. Zonae matrices contain three (mouse) or four (human) glycoproteins (ZP1–4), but which protein binds sperm remains controversial. A defining characteristic of an ess...

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Detalles Bibliográficos
Autores principales: Avella, Matteo A., Baibakov, Boris, Dean, Jurrien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068139/
https://www.ncbi.nlm.nih.gov/pubmed/24934154
http://dx.doi.org/10.1083/jcb.201404025