Cargando…
A single domain of the ZP2 zona pellucida protein mediates gamete recognition in mice and humans
The extracellular zona pellucida surrounds ovulated eggs and mediates gamete recognition that is essential for mammalian fertilization. Zonae matrices contain three (mouse) or four (human) glycoproteins (ZP1–4), but which protein binds sperm remains controversial. A defining characteristic of an ess...
Autores principales: | Avella, Matteo A., Baibakov, Boris, Dean, Jurrien |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068139/ https://www.ncbi.nlm.nih.gov/pubmed/24934154 http://dx.doi.org/10.1083/jcb.201404025 |
Ejemplares similares
-
Human sperm bind to the N-terminal domain of ZP2 in humanized zonae pellucidae in transgenic mice
por: Baibakov, Boris, et al.
Publicado: (2012) -
Ovastacin, a cortical granule protease, cleaves ZP2 in the zona pellucida to prevent polyspermy
por: Burkart, Anna D., et al.
Publicado: (2012) -
ZP4 Is Present in Murine Zona Pellucida and Is Not Responsible for the Specific Gamete Interaction
por: Izquierdo-Rico, Mª José, et al.
Publicado: (2021) -
Molecular Evolutionary Analysis of Nematode Zona Pellucida (ZP) Modules Reveals Disulfide-Bond Reshuffling and Standalone ZP-C Domains
por: Weadick, Cameron J
Publicado: (2020) -
Structural Analysis of Peptide-Analogues of Human Zona Pellucida ZP1 Protein with Amyloidogenic Properties: Insights into Mammalian Zona Pellucida Formation
por: Louros, Nikolaos N., et al.
Publicado: (2013)