Monoterpene Glycoside ESK246 from Pittosporum Targets LAT3 Amino Acid Transport and Prostate Cancer Cell Growth

[Image: see text] The l-type amino acid transporter (LAT) family consists of four members (LAT1–4) that mediate uptake of neutral amino acids including leucine. Leucine is not only important as a building block for proteins, but plays a critical role in mTORC1 signaling leading to protein translatio...

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Detalles Bibliográficos
Autores principales: Wang, Qian, Grkovic, Tanja, Font, Josep, Bonham, Sarah, Pouwer, Rebecca H, Bailey, Charles G, Moran, Anne M, Ryan, Renae M, Rasko, John EJ, Jormakka, Mika, Quinn, Ronald J, Holst, Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068216/
https://www.ncbi.nlm.nih.gov/pubmed/24762008
http://dx.doi.org/10.1021/cb500120x

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