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An Inhibitor’s-Eye View of the ATP-Binding Site of CDKs in Different Regulatory States
[Image: see text] We have used a chemically diverse panel of kinase inhibitors to assess the chemical similarity of the ATP-binding sites of cyclin-dependent kinase (CDK) subfamily members in a range of activation states. Using this approach, we find that different activation states of a particular...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068217/ https://www.ncbi.nlm.nih.gov/pubmed/24669831 http://dx.doi.org/10.1021/cb500135f |