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Gyramides Prevent Bacterial Growth by Inhibiting DNA Gyrase and Altering Chromosome Topology
[Image: see text] Antibiotics targeting DNA gyrase have been a clinical success story for the past half-century, and the emergence of bacterial resistance has fueled the search for new gyrase inhibitors. In this paper we demonstrate that a new class of gyrase inhibitors, the gyramides, are bacterios...
Autores principales: | Rajendram, Manohary, Hurley, Katherine A., Foss, Marie H., Thornton, Kelsey M., Moore, Jared T., Shaw, Jared T., Weibel, Douglas B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068256/ https://www.ncbi.nlm.nih.gov/pubmed/24712739 http://dx.doi.org/10.1021/cb500154m |
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