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Parkinson’s disease-implicated kinases in the brain; insights into disease pathogenesis

Substantial evidence implicates abnormal protein kinase function in various aspects of Parkinson’s disease (PD) etiology. Elevated phosphorylation of the PD-defining pathological protein, α-synuclein, correlates with its aggregation and toxic accumulation in neurons, whilst genetic missense mutation...

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Detalles Bibliográficos
Autores principales:	Dzamko, Nicolas, Zhou, Jinxia, Huang, Yue, Halliday, Glenda M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068290/ https://www.ncbi.nlm.nih.gov/pubmed/25009465 http://dx.doi.org/10.3389/fnmol.2014.00057

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