Cargando…

Towards translational therapies for multiple system atrophy

Multiple system atrophy (MSA) is a fatal adult-onset neurodegenerative disorder of uncertain etiopathogenesis manifesting with autonomic failure, parkinsonism, and ataxia in any combination. The underlying neuropathology affects central autonomic, striatonigral and olivopontocerebellar pathways and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kuzdas-Wood, Daniela, Stefanova, Nadia, Jellinger, Kurt A., Seppi, Klaus, Schlossmacher, Michael G., Poewe, Werner, Wenning, Gregor K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Pergamon Press 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068324/ https://www.ncbi.nlm.nih.gov/pubmed/24598411 http://dx.doi.org/10.1016/j.pneurobio.2014.02.007

Ejemplares similares

Multiple system atrophy as emerging template for accelerated drug discovery in α-synucleinopathies
por: Krismer, Florian, et al.
Publicado: (2014)

Progressive striatonigral degeneration in a transgenic mouse model of multiple system atrophy: translational implications for interventional therapies
por: Refolo, Violetta, et al.
Publicado: (2018)

Disease-Modifying Therapies for Multiple System Atrophy: Where Are We in 2022?
por: Sidoroff, Victoria, et al.
Publicado: (2022)

Is Multiple System Atrophy a Prion-like Disorder?
por: Jellinger, Kurt A., et al.
Publicado: (2021)

Involvement of Peripheral Nerves in the Transgenic PLP-α-Syn Model of Multiple System Atrophy: Extending the Phenotype
por: Kuzdas-Wood, Daniela, et al.
Publicado: (2015)

Intact Olfaction in a Mouse Model of Multiple System Atrophy
por: Krismer, Florian, et al.
Publicado: (2013)

The Relevance of Iron in the Pathogenesis of Multiple System Atrophy: A Viewpoint
por: Kaindlstorfer, Christine, et al.
Publicado: (2018)

Neuroprotection by Epigenetic Modulation in a Transgenic Model of Multiple System Atrophy
por: Sturm, Edith, et al.
Publicado: (2016)

Anle138b Partly Ameliorates Motor Deficits Despite Failure of Neuroprotection in a Model of Advanced Multiple System Atrophy
por: Fellner, Lisa, et al.
Publicado: (2016)

Systemic proteasome inhibition triggers neurodegeneration in a transgenic mouse model expressing human α-synuclein under oligodendrocyte promoter: implications for multiple system atrophy
por: Stefanova, Nadia, et al.
Publicado: (2012)

Animal models of multiple system atrophy
por: Stefanova, Nadia, et al.
Publicado: (2015)

Diffusion-weighted MRI distinguishes Parkinson disease from the parkinsonian variant of multiple system atrophy: A systematic review and meta-analysis
por: Bajaj, Sweta, et al.
Publicado: (2017)

Morphometric MRI profiles of multiple system atrophy variants and implications for differential diagnosis
por: Krismer, Florian, et al.
Publicado: (2019)

Current experimental disease-modifying therapeutics for multiple system atrophy
por: Lemos, Miguel, et al.
Publicado: (2021)

Automated Analysis of Diffusion‐Weighted Magnetic Resonance Imaging for the Differential Diagnosis of Multiple System Atrophy from Parkinson's Disease
por: Krismer, Florian, et al.
Publicado: (2020)

Commentary: Discriminating α-synuclein strains in parkinson's disease and multiple system atrophy
por: Fellner, Lisa, et al.
Publicado: (2020)

Failure of Neuroprotection Despite Microglial Suppression by Delayed-Start Myeloperoxidase Inhibition in a Model of Advanced Multiple System Atrophy: Clinical Implications
por: Kaindlstorfer, Christine, et al.
Publicado: (2015)

Disease Progression in Multiple System Atrophy—Novel Modeling Framework and Predictive Factors
por: Kühnel, Line, et al.
Publicado: (2022)

Sensitivity to Change and Patient‐Centricity of the Unified Multiple System Atrophy Rating Scale Items: A Data‐Driven Analysis
por: Krismer, Florian, et al.
Publicado: (2022)

Review: Multiple system atrophy: emerging targets for interventional therapies
por: Stefanova, N., et al.
Publicado: (2016)

Family History for Neurodegeneration in Multiple System Atrophy: Does it Indicate Susceptibility?
por: Leys, Fabian, et al.
Publicado: (2022)

Neuropathology of multiple system atrophy: Kurt Jellinger`s legacy
por: Campese, Nicole, et al.
Publicado: (2021)

Cognition in multiple system atrophy: a single‐center cohort study
por: Eschlböck, Sabine, et al.
Publicado: (2020)

Targeted overexpression of human α-synuclein in oligodendroglia induces lesions linked to MSA -like progressive autonomic failure
por: Stemberger, Sylvia, et al.
Publicado: (2010)

Induced pluripotent stem cells in multiple system atrophy: recent developments and scientific challenges
por: Ndayisaba, Alain, et al.
Publicado: (2019)

Correction to: Neuropathology of multiple system atrophy: Kurt Jellinger`s legacy
por: Campese, Nicole, et al.
Publicado: (2021)

Oligodendroglial alpha-synucleinopathy and MSA-like cardiovascular autonomic failure: Experimental evidence
por: Kuzdas, Daniela, et al.
Publicado: (2013)

Cardiac sympathetic innervation in Parkinson’s disease versus multiple system atrophy
por: Eckhardt, Christine, et al.
Publicado: (2022)

Characterization of gait variability in multiple system atrophy and Parkinson’s disease
por: Sidoroff, Victoria, et al.
Publicado: (2020)

Multiple system atrophy with hippocampal pathology
por: Jellinger, Kurt A.
Publicado: (2022)

Heterogeneity of Multiple System Atrophy: An Update
por: Jellinger, Kurt A.
Publicado: (2022)

Overexpression of α-synuclein in oligodendrocytes does not increase susceptibility to focal striatal excitotoxicity
por: Kuzdas-Wood, Daniela, et al.
Publicado: (2015)

Multiple System Atrophy: An Oligodendroglioneural Synucleinopathy(1)
por: Jellinger, Kurt A.
Publicado: (2018)

Evaluation of Multiple System Atrophy Subtypes with FDG-PET
por: Jellinger, Kurt
Publicado: (2021)

Mesenchymal Stem Cells in a Transgenic Mouse Model of Multiple System Atrophy: Immunomodulation and Neuroprotection
por: Stemberger, Sylvia, et al.
Publicado: (2011)

A multiplex pedigree with pathologically confirmed multiple system atrophy and Parkinson’s disease with dementia
por: Fanciulli, Alessandra, et al.
Publicado: (2022)

Urodynamic Evaluation in Multiple System Atrophy: A Retrospective Cohort Study
por: Eschlböck, Sabine, et al.
Publicado: (2021)

Changes in the miRNA-mRNA Regulatory Network Precede Motor Symptoms in a Mouse Model of Multiple System Atrophy: Clinical Implications
por: Schafferer, Simon, et al.
Publicado: (2016)

Multiple System Atrophy: Genetic or Epigenetic?
por: Sturm, Edith, et al.
Publicado: (2014)

The Movement Disorder Society Criteria for the Diagnosis of Multiple System Atrophy
por: Wenning, Gregor K., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_b57futm8el6101mc5lor76m0md