Cargando…
Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk
Known genetic loci explain only a small proportion of the familial relative risk of colorectal cancer (CRC). We conducted the largest genome-wide association study in East Asians with 14,963 CRC cases and 31,945 controls and identified six new loci associated with CRC risk (P = 3.42 × 10(−8) to 9.22...
Autores principales: | Zhang, Ben, Jia, Wei-Hua, Matsuda, Koichi, Kweon, Sun-Seog, Matsuo, Keitaro, Xiang, Yong-Bing, Shin, Aesun, Jee, Sun Ha, Kim, Dong-Hyun, Cai, Qiuyin, Long, Jirong, Shi, Jiajun, Wen, Wanqing, Yang, Gong, Zhang, Yanfeng, Li, Chun, Li, Bingshan, Guo, Yan, Ren, Zefang, Ji, Bu-Tian, Pan, Zhi-Zhong, Takahashi, Atsushi, Shin, Min-Ho, Matsuda, Fumihiko, Gao, Yu-Tang, Oh, Jae Hwan, Kim, Soriul, Ahn, Yoon-Ok, Chan, Andrew T, Chang-Claude, Jenny, Slattery, Martha L., Gruber, Stephen B., Schumacher, Fredrick R., Stenzel, Stephanie L., Casey, Graham, Kim, Hyeong-Rok, Jeong, Jin-Young, Park, Ji Won, Li, Hong-Lan, Hosono, Satoyo, Cho, Sang-Hee, Kubo, Michiaki, Shu, Xiao-Ou, Zeng, Yi-Xin, Zheng, Wei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068797/ https://www.ncbi.nlm.nih.gov/pubmed/24836286 http://dx.doi.org/10.1038/ng.2985 |
Ejemplares similares
-
Genome-wide association analyses in East Asians identify new susceptibility loci for colorectal cancer
por: Jia, Wei-Hua, et al.
Publicado: (2012) -
Improved Variant Calling Accuracy by Merging Replicates in Whole-Exome Sequencing Studies
por: Zhang, Yanfeng, et al.
Publicado: (2014) -
IGFBP3 mRNA expression in benign and malignant breast tumors
por: Ren, Zefang, et al.
Publicado: (2007) -
Net Survival of Elderly Patients with Gynecological Cancer Aged Over 75 Years in 2006-2008
por: Inoue, Shusaku, et al.
Publicado: (2019) -
Incorporating Polygenic Risk Scores and Nongenetic Risk Factors for Breast Cancer Risk Prediction Among Asian Women
por: Yang, Yaohua, et al.
Publicado: (2022)