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In Silico target fishing: addressing a “Big Data” problem by ligand-based similarity rankings with data fusion

BACKGROUND: Ligand-based in silico target fishing can be used to identify the potential interacting target of bioactive ligands, which is useful for understanding the polypharmacology and safety profile of existing drugs. The underlying principle of the approach is that known bioactive ligands can b...

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Detalles Bibliográficos
Autores principales:	Liu, Xian, Xu, Yuan, Li, Shanshan, Wang, Yulan, Peng, Jianlong, Luo, Cheng, Luo, Xiaomin, Zheng, Mingyue, Chen, Kaixian, Jiang, Hualiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068908/ https://www.ncbi.nlm.nih.gov/pubmed/24976868 http://dx.doi.org/10.1186/1758-2946-6-33

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