Cargando…

Anti-Hypotensive Treatment and Endothelin Blockade Synergistically Antagonize Exercise Fatigue in Rats under Simulated High Altitude

Rapid ascent to high altitude causes illness and fatigue, and there is a demand for effective acute treatments to alleviate such effects. We hypothesized that increased oxygen delivery to the tissue using a combination of a hypertensive agent and an endothelin receptor A antagonist drugs would limit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Radiloff, Daniel, Zhao, Yulin, Boico, Alina, Blueschke, Gert, Palmer, Gregory, Fontanella, Andrew, Dewhirst, Mark, Piantadosi, Claude A., Noveck, Robert, Irwin, David, Hamilton, Karyn, Klitzman, Bruce, Schroeder, Thies
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068990/ https://www.ncbi.nlm.nih.gov/pubmed/24960187 http://dx.doi.org/10.1371/journal.pone.0099309

Ejemplares similares

Enhanced Drug Delivery to the Skin Using Liposomes
por: Blueschke, Gert, et al.
Publicado: (2018)

Safety and Ergogenic Properties of Combined Aminophylline and Ambrisentan in Hypoxia
por: Schroeder, Thies, et al.
Publicado: (2017)

Endothelin Blockade in Diabetic Kidney Disease
por: Anguiano, Lidia, et al.
Publicado: (2015)

Enhanced Cardiorenal Protective Effects of Combining SGLT2 Inhibition, Endothelin Receptor Antagonism and RAS Blockade in Type 2 Diabetic Mice
por: Vergara, Ander, et al.
Publicado: (2022)

Plasma Pro‐Endothelin‐1 Peptide Concentrations Rise in Chronic Kidney Disease and Following Selective Endothelin A Receptor Antagonism
por: Dhaun, Neeraj, et al.
Publicado: (2015)

Dual Endothelin Antagonism with Aprocitentan as a Novel Therapeutic Approach for Resistant Hypertension
por: Heidari Nejad, Sayeh, et al.
Publicado: (2023)

Endothelin Receptor A Blockade Is an Ineffective Treatment for Adriamycin Nephropathy
por: Tan, Roderick J., et al.
Publicado: (2013)

Hypotensive effect of Gentiana floribunda is mediated through Ca(++) antagonism pathway
por: Khan, Arif-ullah, et al.
Publicado: (2012)

Norepinephrine reuptake blockade to treat neurogenic orthostatic hypotension
por: Eisenhofer, Graeme, et al.
Publicado: (2021)

Bradykinin B(2) receptor blockade and intradialytic hypotension
por: Gamboa, Jorge L., et al.
Publicado: (2023)

The association of an adenine insertion variant in the 5’UTR of the endothelin-1 gene with hypertension and orthostatic hypotension
por: Fan, Xiao-han, et al.
Publicado: (2012)

Increased endothelin-1 in colorectal cancer and reduction of tumour growth by ET (A) receptor antagonism
por: Asham, E, et al.
Publicado: (2001)

Endothelin Receptor A Antagonism Attenuates Renal Medullary Blood Flow Impairment in Endotoxemic Pigs
por: Fenhammar, Johan, et al.
Publicado: (2011)

Serial troponin measurements to monitor risk and response to endothelin A antagonism in chronic kidney disease
por: Anand, Atul, et al.
Publicado: (2020)

Endothelin-A Receptor Blockade Inhibits the Effects of Hypoxia on the Newborn Lung Vasculature
por: Ambalavanan, Namasivayam
Publicado: (2006)

What is the impact of endothelin receptor blockade on atrial remodeling in a hypertensive model?
por: Van Wagoner, David R.
Publicado: (2022)

Cardiac Metabolic Deregulation Induced by the Tyrosine Kinase Receptor Inhibitor Sunitinib is rescued by Endothelin Receptor Antagonism
por: Sourdon, Joevin, et al.
Publicado: (2017)

Endothelin A Receptor Blockade Influences Apoptosis and Cellular Proliferation in the Developing Rat Kidney
por: Yoo, Kee Hwan, et al.
Publicado: (2009)

Utility of Alpha-Blockade in a Hypotensive Pheochromocytoma Patient with Myocardial Infarction
por: Wahab, Norasyikin A., et al.
Publicado: (2015)

Erythropoietin Blockade Inhibits the Induction of Tumor Angiogenesis and Progression
por: Hardee, Matthew E., et al.
Publicado: (2007)

Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system
por: Schlosburg, Joel E., et al.
Publicado: (2010)

Effect of dual endothelin receptor blockade on ocular blood flow in patients with glaucoma and healthy subjects
por: Lasta, Michael, et al.
Publicado: (2008)

Anti-inflammatory effects of endothelin receptor blockade in left atrial tissue of spontaneously hypertensive rats
por: Bukowska, A., et al.
Publicado: (2022)

Endothelin antagonism and sodium glucose Co-transporter 2 inhibition. A potential combination therapeutic strategy for COVID-19
por: Fisk, Marie, et al.
Publicado: (2021)

Endothelin
por: Davenport, Anthony P., et al.
Publicado: (2016)

OPTCON3: An Active Learning Control Algorithm for Nonlinear Quadratic Stochastic Problems
por: Blueschke-Nikolaeva, V., et al.
Publicado: (2019)

An Evolutionary Approach to Passive Learning in Optimal Control Problems
por: Blueschke, D., et al.
Publicado: (2020)

Should fiscal policies be centralized in a monetary union? A dynamic game approach
por: Blueschke, Dmitri, et al.
Publicado: (2023)

Dual endothelin-converting enzyme/neutral endopeptidase blockade in rats with D-galactosamine-induced liver failure
por: Hocher, B, et al.
Publicado: (2011)

Transforming growth factor-β inhibition and endothelin receptor blockade in rats with monocrotaline-induced pulmonary hypertension
por: Megalou, Aikaterini J., et al.
Publicado: (2012)

Blockade of endothelin-1 receptor B regulates molecules of the major histocompatibility complex in sickle cell disease
por: Inostroza-Nieves, Yaritza, et al.
Publicado: (2023)

Endothelin and Endothelin Antagonists in Chronic Kidney Disease
por: Kohan, Donald E., et al.
Publicado: (2014)

Nociceptive tolerance is improved by bradykinin receptor B1 antagonism and joint morphology is protected by both endothelin type A and bradykinin receptor B1 antagonism in a surgical model of osteoarthritis
por: Kaufman, Gabriel N, et al.
Publicado: (2011)

Endotheliitis, endothelin, and endothelin receptor blockers in COVID-19
por: Sanghavi, Devang K., et al.
Publicado: (2021)

A surgeon’s assessment of inadequate neuromuscular antagonism in a case of prolonged neuromuscular blockade
por: Lamberg, James J, et al.
Publicado: (2013)

Endothelin-1 (ET-1) blockade improves mesenteric perfusion in a porcine low cardiac output model
por: Burgener, D, et al.
Publicado: (1999)

Endothelin and the podocyte
por: Barton, Matthias, et al.
Publicado: (2012)

Expression of Endothelin-1, Endothelin Receptor-A, and Endothelin Receptor-B in facial melasma compared to adjacent skin
por: da Silva, Carolina Nunhez, et al.
Publicado: (2023)

Refractory Hypotension after Liver Allograft Reperfusion: A Case of Dynamic Left Ventricular Outflow Tract Obstruction
por: Essandoh, Michael, et al.
Publicado: (2016)

Improved Peripheral Perfusion During Endothelin-A Receptor Blockade in Patients With Type 2 Diabetes and Critical Limb Ischemia
por: Kalani, Majid, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_m4e1vo1uc1hqcctub009dhsol2