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Differences in Meiotic Recombination Rates in Childhood Acute Lymphoblastic Leukemia at an MHC Class II Hotspot Close to Disease Associated Haplotypes

Childhood Acute Lymphoblastic Leukemia (ALL) is a malignant lymphoid disease of which B-cell precursor- (BCP) and T-cell- (T) ALL are subtypes. The role of alleles encoded by major histocompatibility loci (MHC) have been examined in a number of previous studies and results indicating weak, multi-all...

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Detalles Bibliográficos
Autores principales: Thompson, Pamela, Urayama, Kevin, Zheng, Jie, Yang, Peng, Ford, Matt, Buffler, Patricia, Chokkalingam, Anand, Lightfoot, Tracy, Taylor, Malcolm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069019/
https://www.ncbi.nlm.nih.gov/pubmed/24959916
http://dx.doi.org/10.1371/journal.pone.0100480

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