Tumor Cell Heterogeneity in Small Cell Lung Cancer (SCLC): Phenotypical and Functional Differences Associated with Epithelial-Mesenchymal Transition (EMT) and DNA Methylation Changes

Small Cell Lung Cancer (SCLC) is a specific subtype of lung cancer presenting as highly metastatic disease with extremely poor prognosis. Despite responding initially well to chemo- or radiotherapy, SCLC almost invariably relapses and develops resistance to chemotherapy. This is suspected to be rela...

Descripción completa

Detalles Bibliográficos
Autores principales: Krohn, Alexander, Ahrens, Theresa, Yalcin, Arzu, Plönes, Till, Wehrle, Julius, Taromi, Sanaz, Wollner, Stefan, Follo, Marie, Brabletz, Thomas, Mani, Sendurai A., Claus, Rainer, Hackanson, Björn, Burger, Meike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069054/
https://www.ncbi.nlm.nih.gov/pubmed/24959847
http://dx.doi.org/10.1371/journal.pone.0100249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069054/
https://www.ncbi.nlm.nih.gov/pubmed/24959847
http://dx.doi.org/10.1371/journal.pone.0100249

Ejemplares similares