Tissue- and Cell-Specific Mitochondrial Defect in Parkin-Deficient Mice

Loss of Parkin, encoded by PARK2 gene, is a major cause of autosomal recessive Parkinson's disease. In Drosophila and mammalian cell models Parkin has been shown in to play a role in various processes essential to maintenance of mitochondrial quality, including mitochondrial dynamics, biogenesi...

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Detalles Bibliográficos
Autores principales: Damiano, Maria, Gautier, Clément A., Bulteau, Anne-Laure, Ferrando-Miguel, Rosa, Gouarne, Caroline, Paoli, Marc Giraudon, Pruss, Rebecca, Auchère, Françoise, L'Hermitte-Stead, Caroline, Bouillaud, Frédéric, Brice, Alexis, Corti, Olga, Lombès, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069072/
https://www.ncbi.nlm.nih.gov/pubmed/24959870
http://dx.doi.org/10.1371/journal.pone.0099898

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