Long-Term Treatment with the Sodium Glucose Cotransporter 2 Inhibitor, Dapagliflozin, Ameliorates Glucose Homeostasis and Diabetic Nephropathy in db/db Mice

Inhibition of sodium glucose cotransporter 2 (SGLT2) has been reported as a new therapeutic strategy for treating diabetes. However, the effect of SGLT2 inhibitors on the kidney is unknown. In addition, whether SGLT2 inhibitors have an anti-inflammatory or antioxidative stress effect is still unclea...

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Detalles Bibliográficos
Autores principales: Terami, Naoto, Ogawa, Daisuke, Tachibana, Hiromi, Hatanaka, Takashi, Wada, Jun, Nakatsuka, Atsuko, Eguchi, Jun, Horiguchi, Chikage Sato, Nishii, Naoko, Yamada, Hiroshi, Takei, Kohji, Makino, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069074/
https://www.ncbi.nlm.nih.gov/pubmed/24960177
http://dx.doi.org/10.1371/journal.pone.0100777

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