Structure-Based Prediction of Asparagine and Aspartate Degradation Sites in Antibody Variable Regions

Monoclonal antibodies (mAbs) and proteins containing antibody domains are the most prevalent class of biotherapeutics in diverse indication areas. Today, established techniques such as immunization or phage display allow for an efficient generation of new mAbs. Besides functional properties, the sta...

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Detalles Bibliográficos
Autores principales: Sydow, Jasmin F., Lipsmeier, Florian, Larraillet, Vincent, Hilger, Maximiliane, Mautz, Bjoern, Mølhøj, Michael, Kuentzer, Jan, Klostermann, Stefan, Schoch, Juergen, Voelger, Hans R., Regula, Joerg T., Cramer, Patrick, Papadimitriou, Apollon, Kettenberger, Hubert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069079/
https://www.ncbi.nlm.nih.gov/pubmed/24959685
http://dx.doi.org/10.1371/journal.pone.0100736

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