Age-related changes in tissue macrophages precede cardiac functional impairment

Cardiac tissue macrophages (cTMs) are abundant in the murine heart but the extent to which the cTM phenotype changes with age is unknown. This study characterizes aging-dependent phenotypic changes in cTM subsets. Using the Cx(3)cr1(GFP/+) mouse reporter line where GFP marks cTMs, and the tissue mac...

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Detalles Bibliográficos
Autores principales: Pinto, Alexander R., Godwin, James W., Chandran, Anjana, Hersey, Lucy, Ilinykh, Alexei, Debuque, Ryan, Wang, Lina, Rosenthal, Nadia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069267/
https://www.ncbi.nlm.nih.gov/pubmed/24861132

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