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Bayesian Estimation of Nonsynonymous/Synonymous Rate Ratios for Pairwise Sequence Comparisons

The nonsynonymous/synonymous rate ratio (ω = d(N)/d(S)) is an important measure of the mode and strength of natural selection acting on nonsynonymous mutations in protein-coding genes. The simplest such analysis is the estimation of the d(N)/d(S) ratio using two sequences. Both heuristic counting me...

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Detalles Bibliográficos
Autores principales:	Angelis, Konstantinos, dos Reis, Mario, Yang, Ziheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Methods
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069626/ https://www.ncbi.nlm.nih.gov/pubmed/24748652 http://dx.doi.org/10.1093/molbev/msu142

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