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Demographics of animal bite victims & management practices in a tertiary care institute in Mumbai, Maharashtra, India

BACKGROUND & OBJECTIVES: Rabies is an important public health problem worldwide and more than 55,000 people die annually of the disease. The King Edward Memorial Hospital, Mumbai, is a tertiary referral centre where a rabies clinic runs 24 hours. In view of lack of information about the demograp...

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Autores principales: Gogtay, N.J., Nagpal, A., Mallad, A., Patel, K., Stimpson, S.J., Belur, A., Thatte, U.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069742/
https://www.ncbi.nlm.nih.gov/pubmed/24820842
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author Gogtay, N.J.
Nagpal, A.
Mallad, A.
Patel, K.
Stimpson, S.J.
Belur, A.
Thatte, U.M.
author_facet Gogtay, N.J.
Nagpal, A.
Mallad, A.
Patel, K.
Stimpson, S.J.
Belur, A.
Thatte, U.M.
author_sort Gogtay, N.J.
collection PubMed
description BACKGROUND & OBJECTIVES: Rabies is an important public health problem worldwide and more than 55,000 people die annually of the disease. The King Edward Memorial Hospital, Mumbai, is a tertiary referral centre where a rabies clinic runs 24 hours. In view of lack of information about the demographics of the disease in an urban environment the present study was carried out. METHODS: Data on 1000 consecutive animal bite victims presenting to the institute in 2010 were collected over a 15 wk period. An electronic database was specially created for capturing information and was modelled on the information available from the WHO expert consultation on rabies, 2005. Economic burden from the patients’ perspective was calculated using both direct and indirect costs. RESULTS: The victims were largely males (771 subjects). The dog was the major biting animal (891, 89.1%). Bites were mainly of Category III (783, 78.3%). One twenty three subjects used indigenous treatments only for local wound care. Of the Category III bites, only 21 of 783 (2.7%) patients were prescribed human rabies immunoglobulin (HRIG) which was primarily for severe bites or bites close to or on the face. A total of 318 patients did not complete the full Essen regime of the vaccine. The median cost to the patient per bite was [Image: see text] 220 (3.5 USD). INTERPRETATION & CONCLUSIONS: Our findings showed that the use of HRIG was low with less than 2 per cent of the Category III patients being prescribed it. As vaccine and HRIG continue to remain expensive, the intradermal vaccine, shorter regimes like the Zagreb regime and monoclonal antibodies may offer safer and cost-effective options in the future. Further studies need to be done in different parts of the country.
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spelling pubmed-40697422014-07-01 Demographics of animal bite victims & management practices in a tertiary care institute in Mumbai, Maharashtra, India Gogtay, N.J. Nagpal, A. Mallad, A. Patel, K. Stimpson, S.J. Belur, A. Thatte, U.M. Indian J Med Res Original Article BACKGROUND & OBJECTIVES: Rabies is an important public health problem worldwide and more than 55,000 people die annually of the disease. The King Edward Memorial Hospital, Mumbai, is a tertiary referral centre where a rabies clinic runs 24 hours. In view of lack of information about the demographics of the disease in an urban environment the present study was carried out. METHODS: Data on 1000 consecutive animal bite victims presenting to the institute in 2010 were collected over a 15 wk period. An electronic database was specially created for capturing information and was modelled on the information available from the WHO expert consultation on rabies, 2005. Economic burden from the patients’ perspective was calculated using both direct and indirect costs. RESULTS: The victims were largely males (771 subjects). The dog was the major biting animal (891, 89.1%). Bites were mainly of Category III (783, 78.3%). One twenty three subjects used indigenous treatments only for local wound care. Of the Category III bites, only 21 of 783 (2.7%) patients were prescribed human rabies immunoglobulin (HRIG) which was primarily for severe bites or bites close to or on the face. A total of 318 patients did not complete the full Essen regime of the vaccine. The median cost to the patient per bite was [Image: see text] 220 (3.5 USD). INTERPRETATION & CONCLUSIONS: Our findings showed that the use of HRIG was low with less than 2 per cent of the Category III patients being prescribed it. As vaccine and HRIG continue to remain expensive, the intradermal vaccine, shorter regimes like the Zagreb regime and monoclonal antibodies may offer safer and cost-effective options in the future. Further studies need to be done in different parts of the country. Medknow Publications & Media Pvt Ltd 2014-03 /pmc/articles/PMC4069742/ /pubmed/24820842 Text en Copyright: © Indian Journal of Medical Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Gogtay, N.J.
Nagpal, A.
Mallad, A.
Patel, K.
Stimpson, S.J.
Belur, A.
Thatte, U.M.
Demographics of animal bite victims & management practices in a tertiary care institute in Mumbai, Maharashtra, India
title Demographics of animal bite victims & management practices in a tertiary care institute in Mumbai, Maharashtra, India
title_full Demographics of animal bite victims & management practices in a tertiary care institute in Mumbai, Maharashtra, India
title_fullStr Demographics of animal bite victims & management practices in a tertiary care institute in Mumbai, Maharashtra, India
title_full_unstemmed Demographics of animal bite victims & management practices in a tertiary care institute in Mumbai, Maharashtra, India
title_short Demographics of animal bite victims & management practices in a tertiary care institute in Mumbai, Maharashtra, India
title_sort demographics of animal bite victims & management practices in a tertiary care institute in mumbai, maharashtra, india
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069742/
https://www.ncbi.nlm.nih.gov/pubmed/24820842
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