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Structure based molecular inhibition of Caspase-8 for treatment of multi-neurodegenerative diseases using known natural compounds
Neurodegenerative disorders are often associated with excessive neuronal apoptosis. It is well known that apoptosis is regulated by some intracellular proteases, such as, Caspases (cysteine-dependent, aspartate-specific proteases). In fact, Caspase-8 which is an initiator caspase, has been identifie...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Biomedical Informatics
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070048/ https://www.ncbi.nlm.nih.gov/pubmed/24966519 http://dx.doi.org/10.6026/97320630010191 |