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Molecular designing and in silico evaluation of darunavir derivatives as anticancer agents

Darunavir is a synthetic nonpeptidic protease inhibitor which has been tested for anticancer properties. To deduce and enhance the anticancer activity of the Darunavir, we have modified its reactive moiety in an effective way. We designed 9 analogues in ChemBioOffice 2010 and minimized using the Lig...

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Detalles Bibliográficos
Autores principales:	Mahto, Manoj kumar, Yellapu, Nanda Kumar, Kilaru, Ravendra Babu, Chamarthi, Naga Raju, Bhaskar, Matcha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Biomedical Informatics 2014
Materias:	Hypothesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070053/ https://www.ncbi.nlm.nih.gov/pubmed/24966524 http://dx.doi.org/10.6026/97320630010221

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