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An extensive analysis of disease-gene associations using network integration and fast kernel-based gene prioritization methods

OBJECTIVE: In the context of “network medicine”, gene prioritization methods represent one of the main tools to discover candidate disease genes by exploiting the large amount of data covering different types of functional relationships between genes. Several works proposed to integrate multiple sou...

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Detalles Bibliográficos
Autores principales: Valentini, Giorgio, Paccanaro, Alberto, Caniza, Horacio, Romero, Alfonso E., Re, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Publishing 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070077/
https://www.ncbi.nlm.nih.gov/pubmed/24726035
http://dx.doi.org/10.1016/j.artmed.2014.03.003