Cargando…

An extensive analysis of disease-gene associations using network integration and fast kernel-based gene prioritization methods

OBJECTIVE: In the context of “network medicine”, gene prioritization methods represent one of the main tools to discover candidate disease genes by exploiting the large amount of data covering different types of functional relationships between genes. Several works proposed to integrate multiple sou...

Descripción completa

Detalles Bibliográficos
Autores principales:	Valentini, Giorgio, Paccanaro, Alberto, Caniza, Horacio, Romero, Alfonso E., Re, Matteo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science Publishing 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070077/ https://www.ncbi.nlm.nih.gov/pubmed/24726035 http://dx.doi.org/10.1016/j.artmed.2014.03.003

Ejemplares similares

A network medicine approach to quantify distance between hereditary disease modules on the interactome
por: Caniza, Horacio, et al.
Publicado: (2015)

GOssTo: a stand-alone application and a web tool for calculating semantic similarities on the Gene Ontology
por: Caniza, Horacio, et al.
Publicado: (2014)

Cancer module genes ranking using kernelized score functions
por: Re, Matteo, et al.
Publicado: (2012)

Scuba: scalable kernel-based gene prioritization
por: Zampieri, Guido, et al.
Publicado: (2018)

Heterogeneous data integration methods for patient similarity networks
por: Gliozzo, Jessica, et al.
Publicado: (2022)

Network modeling of patients' biomolecular profiles for clinical phenotype/outcome prediction
por: Gliozzo, Jessica, et al.
Publicado: (2020)

The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function
por: Warde-Farley, David, et al.
Publicado: (2010)

Integrating gene expression and protein-protein interaction network to prioritize cancer-associated genes
por: Wu, Chao, et al.
Publicado: (2012)

An integrated network of Arabidopsis growth regulators and its use for gene prioritization
por: Sabaghian, Ehsan, et al.
Publicado: (2015)

Network-based integration of multi-omics data for prioritizing cancer genes
por: Dimitrakopoulos, Christos, et al.
Publicado: (2018)

Integrating omics data and protein interaction networks to prioritize driver genes in cancer
por: Zhang, Tiejun, et al.
Publicado: (2017)

Network Diffusion-Based Prioritization of Autism Risk Genes Identifies Significantly Connected Gene Modules
por: Mosca, Ettore, et al.
Publicado: (2017)

Network Propagation with Dual Flow for Gene Prioritization
por: Wu, Shunyao, et al.
Publicado: (2015)

Prioritization of Susceptibility Genes for Ectopic Pregnancy by Gene Network Analysis
por: Liu, Ji-Long, et al.
Publicado: (2016)

SCPS: a fast implementation of a spectral method for detecting protein families on a genome-wide scale
por: Nepusz, Tamás, et al.
Publicado: (2010)

Network Based Integrated Analysis of Phenotype-Genotype Data for Prioritization of Candidate Symptom Genes
por: Li, Xing, et al.
Publicado: (2014)

NERI: network-medicine based integrative approach for disease gene prioritization by relative importance
por: Simões, Sérgio N, et al.
Publicado: (2015)

In Silico Gene Prioritization by Integrating Multiple Data Sources
por: Chen, Yixuan, et al.
Publicado: (2011)

Integrating human omics data to prioritize candidate genes
por: Chen, Yong, et al.
Publicado: (2013)

NetworkPrioritizer: a versatile tool for network-based prioritization of candidate disease genes or other molecules
por: Kacprowski, Tim, et al.
Publicado: (2013)

Disease gene prediction for molecularly uncharacterized diseases
por: Cáceres, Juan J., et al.
Publicado: (2019)

Harnessing Gene Expression Networks to Prioritize Candidate Epileptic Encephalopathy Genes
por: Oliver, Karen L., et al.
Publicado: (2014)

Prioritizing Susceptible Genes for Thyroid Cancer Based on Gene Interaction Network
por: Zhong, Lin-kun, et al.
Publicado: (2021)

Pathway-Dependent Effectiveness of Network Algorithms for Gene Prioritization
por: Shim, Jung Eun, et al.
Publicado: (2015)

Heterogeneous Network Edge Prediction: A Data Integration Approach to Prioritize Disease-Associated Genes
por: Himmelstein, Daniel S., et al.
Publicado: (2015)

Prioritizing Candidate Genes for Type 2 Diabetes Mellitus using Integrated Network and Pathway Analysis
por: Prakash, Tejaswini, et al.
Publicado: (2022)

Kernel size‐related genes revealed by an integrated eQTL analysis during early maize kernel development
por: Pang, Junling, et al.
Publicado: (2019)

Disease gene prioritization by integrating tissue-specific molecular networks using a robust multi-network model
por: Ni, Jingchao, et al.
Publicado: (2016)

Think globally and solve locally: secondary memory-based network learning for automated multi-species function prediction
por: Mesiti, Marco, et al.
Publicado: (2014)

Network hub-node prioritization of gene regulation with intra-network association
por: Chang, Hung-Ching, et al.
Publicado: (2020)

Benchmarking network-based gene prioritization methods for cerebral small vessel disease
por: Zhang, Huayu, et al.
Publicado: (2021)

PhenoGeneRanker: Gene and Phenotype Prioritization Using Multiplex Heterogeneous Networks
por: Dursun, Cagatay, et al.
Publicado: (2022)

A Comparison of Gene Set Analysis Methods in Terms of Sensitivity, Prioritization and Specificity
por: Tarca, Adi L., et al.
Publicado: (2013)

Integrating multiple protein-protein interaction networks to prioritize disease genes: a Bayesian regression approach
por: Zhang, Wangshu, et al.
Publicado: (2011)

Gene prioritization, communality analysis, networking and metabolic integrated pathway to better understand breast cancer pathogenesis
por: López-Cortés, Andrés, et al.
Publicado: (2018)

Tissue-Specific Functional Networks for Prioritizing Phenotype and Disease Genes
por: Guan, Yuanfang, et al.
Publicado: (2012)

Drug target prioritization by perturbed gene expression and network information
por: Isik, Zerrin, et al.
Publicado: (2015)

A Comprehensive Evaluation of Disease Phenotype Networks for Gene Prioritization
por: Li, Jianhua, et al.
Publicado: (2016)

Prioritizing transcriptional factors in gene regulatory networks with PageRank
por: Ding, Hongxu, et al.
Publicado: (2020)

Gene Prioritization by Integrated Analysis of Protein Structural and Network Topological Properties for the Protein-Protein Interaction Network of Neurological Disorders
por: Paul, Yashna, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_b4nkvqb2qru7icosupkqbapd1k