Peptide receptor radionuclide therapy (PRRT) with [(177)Lu-DOTA(0),Tyr(3)]octreotate in combination with RAD001 treatment: further investigations on tumor metastasis and response in the rat pancreatic CA20948 tumor model

BACKGROUND: Previously, we reported on the unexpected development of distant metastases in the subcutaneous rat pancreas CA20948 tumor model after 4.5 weeks of treatment with RAD001-only or in combination with [(177)Lu-DOTA(0),Tyr(3)]octreotate ((177)Lu-DOTATATE) (Cancer Res. 73:12-8, 2013). Moreove...

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Detalles Bibliográficos
Autores principales: Bison, Sander M, Pool, Stefan E, Koelewijn, Stuart J, van der Graaf, Linda M, Groen, Harald C, Melis, Marleen, de Jong, Marion
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070081/
https://www.ncbi.nlm.nih.gov/pubmed/24995150
http://dx.doi.org/10.1186/s13550-014-0021-y

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