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Diabetic cardiomyopathy is associated with defective myocellular copper regulation and both defects are rectified by divalent copper chelation
BACKGROUND: Heart disease is the leading cause of death in diabetic patients, and defective copper metabolism may play important roles in the pathogenesis of diabetic cardiomyopathy (DCM). The present study sought to determine how myocardial copper status and key copper-proteins might become impaire...
Autores principales: | Zhang, Shaoping, Liu, Hong, Amarsingh, Greeshma V, Cheung, Carlos C H, Hogl, Sebastian, Narayanan, Umayal, Zhang, Lin, McHarg, Selina, Xu, Jingshu, Gong, Deming, Kennedy, John, Barry, Bernard, Choong, Yee Soon, Phillips, Anthony R J, Cooper, Garth J S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070334/ https://www.ncbi.nlm.nih.gov/pubmed/24927960 http://dx.doi.org/10.1186/1475-2840-13-100 |
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