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Valproate-Induced Liver Injury: Modulation by the Omega-3 Fatty Acid DHA Proposes a Novel Anticonvulsant Regimen

BACKGROUND: The polyunsaturated, ω-3 fatty acid, docosahexaenoic acid (DHA), claims diverse cytoprotective potentials, although via largely undefined triggers. Thus, we currently first tested the ability of DHA to ameliorate valproate (VPA)-evoked hepatotoxicity, to modulate its anticonvulsant effec...

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Detalles Bibliográficos
Autores principales:	Abdel-Dayem, Marwa A., Elmarakby, Ahmed A., Abdel-Aziz, Azza A., Pye, Chelsey, Said, Shehta A., El-Mowafy, Abdalla M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2014
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070460/ https://www.ncbi.nlm.nih.gov/pubmed/24733439 http://dx.doi.org/10.1007/s40268-014-0042-z

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