Correlation Between Trough Plasma Dabigatran Concentrations and Estimates of Glomerular Filtration Rate Based on Creatinine and Cystatin C

AIMS: Dabigatran is largely cleared by renal excretion. Renal function is thus a major determinant of trough dabigatran concentrations, which correlate with the risk of thromboembolic and haemorrhagic outcomes. Current dabigatran dosing guidelines use the Cockcroft–Gault (CG) equation to gauge renal...

Descripción completa

Detalles Bibliográficos
Autores principales: Chin, Paul K. L., Wright, Daniel F. B., Zhang, Mei, Wallace, Mary C., Roberts, Rebecca L., Patterson, David M., Jensen, Berit P., Barclay, Murray L., Begg, Evan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2014
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070467/
https://www.ncbi.nlm.nih.gov/pubmed/24797400
http://dx.doi.org/10.1007/s40268-014-0045-9

Ejemplares similares

Ejemplares similares