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Patterns of sequencing coverage bias revealed by ultra-deep sequencing of vertebrate mitochondria

BACKGROUND: Genome and transcriptome sequencing applications that rely on variation in sequence depth can be negatively affected if there are systematic biases in coverage. We have investigated patterns of local variation in sequencing coverage by utilising ultra-deep sequencing (>100,000X) of mt...

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Detalles Bibliográficos
Autores principales:	Ekblom, Robert, Smeds, Linnéa, Ellegren, Hans
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070552/ https://www.ncbi.nlm.nih.gov/pubmed/24923674 http://dx.doi.org/10.1186/1471-2164-15-467

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