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Caffeic Acid Phenethylester Increases Stress Resistance and Enhances Lifespan in Caenorhabditis elegans by Modulation of the Insulin-Like DAF-16 Signalling Pathway
CAPE is an active constituent of propolis which is widely used in traditional medicine. This hydroxycinnamic acid derivate is a known activator of the redox-active Nrf2 signalling pathway in mammalian cells. We used C. elegans to investigate the effects of this compound on accumulation of reactive o...
Autores principales: | Havermann, Susannah, Chovolou, Yvonni, Humpf, Hans-Ulrich, Wätjen, Wim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070918/ https://www.ncbi.nlm.nih.gov/pubmed/24964141 http://dx.doi.org/10.1371/journal.pone.0100256 |
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