Single-Step Selection of Bivalent Aptamers Validated by Comparison with SELEX Using High-Throughput Sequencing

The identification of nucleic acid aptamers would be advanced if they could be obtained after fewer rounds of selection and amplification. In this paper the identification of bivalent aptamers for thrombin by SELEX and single-step selection are compared using next generation sequencing and motif fin...

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Detalles Bibliográficos
Autores principales: Wilson, Robert, Bourne, Christian, Chaudhuri, Roy R., Gregory, Richard, Kenny, John, Cossins, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070925/
https://www.ncbi.nlm.nih.gov/pubmed/24963654
http://dx.doi.org/10.1371/journal.pone.0100572

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