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MK2 and Fas Receptor Contribute to the Severity of CNS Demyelination

Models of inflammatory or degenerative diseases demonstrated that the protein-kinase MK2 is a key player in inflammation. In this study we examined the role of MK2 in MOG(35-55)-induced experimental autoimmune encephalomyelitis (EAE), the animal model for multiple sclerosis. In MK2-deficient (MK2(−/...

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Detalles Bibliográficos
Autores principales: Tietz, Silvia M., Hofmann, Regina, Thomas, Tobias, Tackenberg, Björn, Gaestel, Matthias, Berghoff, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070940/
https://www.ncbi.nlm.nih.gov/pubmed/24964076
http://dx.doi.org/10.1371/journal.pone.0100363