Cargando…

pH-Sensitive Nanomicelles for Controlled and Efficient Drug Delivery to Human Colorectal Carcinoma LoVo Cells

BACKGROUND: The triblock copolymers PEG-P(Asp-DIP)-P(Lys-Ca) (PEALCa) of polyethylene glycol (PEG), poly(N-(N’,N’-diisopropylaminoethyl) aspartamide) (P(Asp-DIP)), and poly (lysine-cholic acid) (P(Lys-Ca)) were synthesized as a pH-sensitive drug delivery system. In neutral aqueous environment such a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Feng, Shi-Ting, Li, Jingguo, Luo, Yanji, Yin, Tinghui, Cai, Huasong, Wang, Yong, Dong, Zhi, Shuai, Xintao, Li, Zi-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071001/ https://www.ncbi.nlm.nih.gov/pubmed/24964012 http://dx.doi.org/10.1371/journal.pone.0100732

Ejemplares similares

Gene Expression Profile of the Human Colorectal Carcinoma LoVo Cells Treated With Sporamin and Thapsigargin
por: Yang, Chun, et al.
Publicado: (2021)

Laminarin-induced apoptosis in human colon cancer LoVo cells
por: JI, CHEN-FENG, et al.
Publicado: (2014)

Effects of ADMA on gene expression and metabolism in serum-starved LoVo cells
por: Zheng, Ningning, et al.
Publicado: (2016)

Magnesium homeostasis in colon carcinoma LoVo cells sensitive or resistant to doxorubicin
por: Castiglioni, Sara, et al.
Publicado: (2015)

In-Vitro and In-Silico Evaluations of Heterocyclic-Containing Diarylpentanoids as Bcl-2 Inhibitors Against LoVo Colorectal Cancer Cells
por: Leong, Sze Wei, et al.
Publicado: (2020)

Butyrate modulates mucin secretion and bacterial adherence in LoVo cells via MAPK signaling
por: Jung, Tae-Hwan, et al.
Publicado: (2022)

Metformin suppressed the proliferation of LoVo cells and induced a time-dependent metabolic and transcriptional alteration
por: He, Jiaojiao, et al.
Publicado: (2015)

Regulation of survivin and caspase/Bcl-2/Cyto-C signaling by TDB-6 induces apoptosis of colorectal carcinoma LoVo cells
por: Shi, Xianpeng, et al.
Publicado: (2022)

Synergistic antitumor effects of polysaccharides and anthocyanins from Lycium ruthenicum Murr. on human colorectal carcinoma LoVo cells and the molecular mechanism
por: Qin, Xinshu, et al.
Publicado: (2022)

Microparticles vs. Macroparticles as Curcumin Delivery Vehicles: Structural Studies and Cytotoxic Effect in Human Adenocarcinoma Cell Line (LoVo)
por: Wezgowiec, Joanna, et al.
Publicado: (2021)

Effect of API-1 and FR180204 on cell proliferation and apoptosis in human DLD-1 and LoVo colorectal cancer cells
por: Saglam, Atiye Seda Yar, et al.
Publicado: (2016)

Transcriptome Analysis and Autophagy Investigation of LoVo Cells Stimulated with Exosomes Derived from T. asiatica Adult Worms
por: Liang, Panhong, et al.
Publicado: (2021)

Characterisation of a LoVo subline resistant to a benzoyl mustard derivative of distamycin A (FCE 24517).
por: Capolongo, L., et al.
Publicado: (1993)

Maize polyamine oxidase in the presence of spermine/spermidine induces the apoptosis of LoVo human colon adenocarcinoma cells
por: Ohkubo, Shinji, et al.
Publicado: (2019)

ROS-Mediated Apoptotic Cell Death of Human Colon Cancer LoVo Cells by Milk δ-Valerobetaine
por: D’Onofrio, Nunzia, et al.
Publicado: (2020)

N-Hydroxyphthalimide exhibits antitumor activity by suppressing mTOR signaling pathway in BT-20 and LoVo cells
por: Wang, Min, et al.
Publicado: (2016)

Hederagenin from the leaves of ivy (Hedera helix L.) induces apoptosis in human LoVo colon cells through the mitochondrial pathway
por: Liu, Bao-Xin-Zi, et al.
Publicado: (2014)

Network Pharmacology Analysis and Experiments Validation of the Inhibitory Effect of JianPi Fu Recipe on Colorectal Cancer LoVo Cells Metastasis and Growth
por: Lu, Xinyi, et al.
Publicado: (2020)

6-Gingerol Inhibits Growth of Colon Cancer Cell LoVo via Induction of G2/M Arrest
por: Lin, Ching-Bin, et al.
Publicado: (2012)

Effects of silencing RIP1 with siRNA on the biological behavior of the LoVo human colon cancer cell line
por: YOU, HONG-XIA, et al.
Publicado: (2014)

Ginsenoside-Rp1-induced apolipoprotein A-1 expression in the LoVo human colon cancer cell line
por: Kim, Mi-Yeon, et al.
Publicado: (2014)

Effects of Artonin E on Cell Growth Inhibition and Apoptosis Induction in Colon Cancer LoVo and HCT116 Cells
por: Yangnok, Kanyaluck, et al.
Publicado: (2022)

DDR1 promotes LoVo cell proliferation by regulatingenergy metabolism: Effect of DDR1 on CRC cell metabolic reprogramming
por: Xiong, Bin, et al.
Publicado: (2022)

Curcumol Inhibits Growth and Induces Apoptosis of Colorectal Cancer LoVo Cell Line via IGF-1R and p38 MAPK Pathway
por: Wang, Juan, et al.
Publicado: (2015)

Acetylshikonin Induces Apoptosis in Human Colorectal Cancer HCT-15 and LoVo Cells via Nuclear Translocation of FOXO3 and ROS Level Elevation
por: Lim, Heui Min, et al.
Publicado: (2021)

Overexpression of lamin B1 induces mitotic catastrophe in colon cancer LoVo cells and is associated with worse clinical outcomes
por: Izdebska, Magdalena, et al.
Publicado: (2017)

Thymoquinone suppresses migration of LoVo human colon cancer cells by reducing prostaglandin E2 induced COX-2 activation
por: Hsu, Hsi-Hsien, et al.
Publicado: (2017)

Augmented O‐GlcNAcylation of AMP‐activated kinase promotes the proliferation of LoVo cells, a colon cancer cell line
por: Ishimura, Emi, et al.
Publicado: (2017)

A new method for the study of biophysical and morphological parameters in 3D cell cultures: Evaluation in LoVo spheroids treated with crizotinib
por: Sargenti, Azzurra, et al.
Publicado: (2021)

A Comparison of Doxorubicin-Resistant Colon Cancer LoVo and Leukemia HL60 Cells: Common Features, Different Underlying Mechanisms
por: Locatelli, Laura, et al.
Publicado: (2021)

Different vimentin expression in two clones derived from a human colocarcinoma cell line (LoVo) showing different sensitivity to doxorubicin.
por: Conforti, G., et al.
Publicado: (1995)

Inhibition of protein kinase C-alpha isoform enhances the P-glycoprotein expression and the survival of LoVo human colon adenocarcinoma cells to doxorubicin exposure.
por: La Porta, C. A., et al.
Publicado: (1998)

Dichloroacetate induces protective autophagy in LoVo cells: involvement of cathepsin D/thioredoxin-like protein 1 and Akt-mTOR-mediated signaling
por: Gong, F, et al.
Publicado: (2013)

Prostaglandin E2-Induced COX-2 Expressions via EP2 and EP4 Signaling Pathways in Human LoVo Colon Cancer Cells
por: Hsu, Hsi-Hsien, et al.
Publicado: (2017)

Downregulation of miR-222-3p Reverses Doxorubicin-Resistance in LoVo Cells Through Upregulating Forkhead Box Protein P2 (FOXP2) Protein
por: Wang, Huaiming, et al.
Publicado: (2019)

Crosstalk between p38 MAPK and caspase-9 regulates mitochondria-mediated apoptosis induced by tetra-α-(4-carboxyphenoxy) phthalocyanine zinc photodynamic therapy in LoVo cells
por: Wang, Yu, et al.
Publicado: (2018)

PRL-3 promotes the motility, invasion, and metastasis of LoVo colon cancer cells through PRL-3-integrin β1-ERK1/2 and-MMP2 signaling
por: Peng, Lirong, et al.
Publicado: (2009)

Discoidin domain receptor 1a (DDR1a) confers 5-fluorouracil cytotoxicity in LoVo cell via PI3K/AKT/Bcl-2 pathway
por: Xiong, Bin, et al.
Publicado: (2022)

Alpha-2-Glycoprotein 1(AZGP1) Regulates Biological Behaviors of LoVo Cells by Down-Regulating mTOR Signaling Pathway and Endogenous Fatty Acid Synthesis
por: Chang, Ligong, et al.
Publicado: (2014)

JNK suppression is essential for 17β-Estradiol inhibits prostaglandin E2-Induced uPA and MMP-9 expressions and cell migration in human LoVo colon cancer cells
por: Hsu, Hsi-Hsien, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_1ukli2sqh57930busr0nka5a4c