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Glucose-Regulated Protein 78 (Grp78) Confers Chemoresistance to Tumor Endothelial Cells under Acidic Stress

OBJECTIVES: This study was designed to investigate the activation of the unfolded protein response (UPR) in tumor associated endothelial cells (TECs) and its association with chemoresistance during acidic pH stress. MATERIALS AND METHODS: Endothelial cells from human oral squamous cell carcinomas (O...

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Detalles Bibliográficos
Autores principales: Visioli, Fernanda, Wang, Yugang, Alam, Goleeta N., Ning, Yu, Rados, Pantelis V., Nör, Jacques E., Polverini, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071032/
https://www.ncbi.nlm.nih.gov/pubmed/24964091
http://dx.doi.org/10.1371/journal.pone.0101053