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Exaggerated renal fibrosis in P2X4 receptor-deficient mice following unilateral ureteric obstruction

BACKGROUND: The ATP-sensitive P2X7 receptor (P2X7R) has been shown to contribute to renal injury in nephrotoxic nephritis, a rodent model of acute glomerulonephritis, and in unilateral ureteric obstruction (UUO), a rodent model of chronic interstitial inflammation and fibrosis. Renal tubular cells,...

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Detalles Bibliográficos
Autores principales:	Kim, Min Jeong, Turner, Clare M., Hewitt, Reiko, Smith, Jennifer, Bhangal, Gurjeet, Pusey, Charles D., Unwin, Robert J., Tam, Frederick W.K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071051/ https://www.ncbi.nlm.nih.gov/pubmed/24574541 http://dx.doi.org/10.1093/ndt/gfu019

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