Ameliorative Effect of a Selective Endothelin ET(A) Receptor Antagonist in Rat Model of L-Methionine-induced Vascular Dementia

The present study was designed to investigate the efficacy of selective ET(A) receptor antagonist, ambrisentan on hyperhomocysteinemia-induced experimental vascular dementia. L-methionine was administered for 8 weeks to induce hyperhomocysteinemia and associated vascular dementia in male rats. Ambri...

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Detalles Bibliográficos
Autores principales: Mangat, Gautamjeet S, Jaggi, Amteshwar S, Singh, Nirmal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071172/
https://www.ncbi.nlm.nih.gov/pubmed/24976759
http://dx.doi.org/10.4196/kjpp.2014.18.3.201

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