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RNA-seq: impact of RNA degradation on transcript quantification

BACKGROUND: The use of low quality RNA samples in whole-genome gene expression profiling remains controversial. It is unclear if transcript degradation in low quality RNA samples occurs uniformly, in which case the effects of degradation can be corrected via data normalization, or whether different...

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Detalles Bibliográficos
Autores principales:	Gallego Romero, Irene, Pai, Athma A, Tung, Jenny, Gilad, Yoav
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071332/ https://www.ncbi.nlm.nih.gov/pubmed/24885439 http://dx.doi.org/10.1186/1741-7007-12-42

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