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Ilimaquinone and Ethylsmenoquinone, Marine Sponge Metabolites, Suppress the Proliferation of Multiple Myeloma Cells by Down-Regulating the Level of β-Catenin
Deregulation of Wnt/β-catenin signaling promotes the development of a broad range of human cancers, including multiple myeloma, and is thus a potential target for the development of therapeutics for this disease. Here, we used a cell-based reporter system to demonstrate that ilimaquinone and ethylsm...
Autores principales: | Park, Seoyoung, Yun, Eunju, Hwang, In Hyun, Yoon, Soojin, Kim, Dong-Eun, Kim, Ji Seon, Na, MinKyun, Song, Gyu-Yong, Oh, Sangtaek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071574/ https://www.ncbi.nlm.nih.gov/pubmed/24879546 http://dx.doi.org/10.3390/md12063231 |
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