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Quinone and Hydroquinone Metabolites from the Ascidians of the Genus Aplidium

Ascidians of the genus Aplidium are recognized as an important source of chemical diversity and bioactive natural products. Among the compounds produced by this genus are non-nitrogenous metabolites, mainly prenylated quinones and hydroquinones. This review discusses the isolation, structural elucid...

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Detalles Bibliográficos
Autores principales: Bertanha, Camila Spereta, Januário, Ana Helena, Alvarenga, Tavane Aparecida, Pimenta, Letícia Pereira, e Silva, Márcio Luis Andrade, Cunha, Wilson Roberto, Pauletti, Patrícia Mendonça
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071593/
https://www.ncbi.nlm.nih.gov/pubmed/24927227
http://dx.doi.org/10.3390/md12063608
Descripción
Sumario:Ascidians of the genus Aplidium are recognized as an important source of chemical diversity and bioactive natural products. Among the compounds produced by this genus are non-nitrogenous metabolites, mainly prenylated quinones and hydroquinones. This review discusses the isolation, structural elucidation, and biological activities of quinones, hydroquinones, rossinones, longithorones, longithorols, floresolides, scabellones, conicaquinones, aplidinones, thiaplidiaquinones, and conithiaquinones. A compilation of the (13)C-NMR spectral data of these compounds is also presented.