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Aberrant Proliferation of Differentiating Alveolar Cells Induces Hyperplasia in Resting Mammary Glands of SV40-TAg Transgenic Mice

WAP-T1 transgenic mice express SV40-TAg under control of the whey acidic protein (WAP) promoter, which directs activity of this strong viral oncogene to luminal cells of the mammary gland. Resting uniparous WAP-T1 glands develop hyperplasia composed of TAg positive cells prior to appearance of advan...

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Detalles Bibliográficos
Autores principales:	Quante, Timo, Wegwitz, Florian, Abe, Julia, Rossi, Alessandra, Deppert, Wolfgang, Bohn, Wolfgang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071642/ https://www.ncbi.nlm.nih.gov/pubmed/25019062 http://dx.doi.org/10.3389/fonc.2014.00168

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