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Successful pregnancy outcome after in vitro fertilisation following Pre-implantation Genetic Diagnosis/Polymerase Chain Reaction screening for single gene disorder (sickle cell anaemia) before embryo transfer: The clinical experience of an in vitro fertilisation clinic in Nigeria

A couple, both carriers of the sickle cell anaemia trait (Genotype HbAS) with an offspring already affected with the genetic disease underwent a Pre-implantation Genetic Diagnosis/Polymerase Chain Reaction screening of biopsied blastomeres. DNA analysis of single blastomeres was carried out to find...

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Detalles Bibliográficos
Autores principales: Okeke, Chizara, Ailoje-Ibru, Kemi, Olukoya, Kemi, Ogbeche, Rose, Adewusi, Abiola, Iloabachie, Ebele, Ashiru, Oladapo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071672/
https://www.ncbi.nlm.nih.gov/pubmed/24970979
http://dx.doi.org/10.4103/0300-1652.128181