Management of life-threatening calcium channel blocker overdose with continuous veno-venous hemodiafiltration with charcoal hemoperfusion

Cases of calcium channel blocker overdose reported from India are few, and although rare, they are associated with high mortality. Management includes fluids, vasopressors, calcium gluconate or chloride, glucagon infusion, and hyperinsulinemia-euglycemia therapy along with some rescue therapies trie...

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Autores principales: Garg, Suneel K., Goyal, Pankaj K., Kumar, Rahul, Juneja, Deven, Bhasin, Alka, Singh, Omender
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071686/
https://www.ncbi.nlm.nih.gov/pubmed/24987241
http://dx.doi.org/10.4103/0972-5229.133939
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author Garg, Suneel K.
Goyal, Pankaj K.
Kumar, Rahul
Juneja, Deven
Bhasin, Alka
Singh, Omender
author_facet Garg, Suneel K.
Goyal, Pankaj K.
Kumar, Rahul
Juneja, Deven
Bhasin, Alka
Singh, Omender
author_sort Garg, Suneel K.
collection PubMed
description Cases of calcium channel blocker overdose reported from India are few, and although rare, they are associated with high mortality. Management includes fluids, vasopressors, calcium gluconate or chloride, glucagon infusion, and hyperinsulinemia-euglycemia therapy along with some rescue therapies tried in anecdotal reports. We report here a case of life-threatening overdose of amlodipine with shock, refractory to conventional therapies. Salvage therapy with continuous veno-venous hemodiafiltration using charcoal hemoperfusion with prior infusion of intravenous lipid emulsion resulted in a successful outcome.
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spelling pubmed-40716862014-07-01 Management of life-threatening calcium channel blocker overdose with continuous veno-venous hemodiafiltration with charcoal hemoperfusion Garg, Suneel K. Goyal, Pankaj K. Kumar, Rahul Juneja, Deven Bhasin, Alka Singh, Omender Indian J Crit Care Med Case Report Cases of calcium channel blocker overdose reported from India are few, and although rare, they are associated with high mortality. Management includes fluids, vasopressors, calcium gluconate or chloride, glucagon infusion, and hyperinsulinemia-euglycemia therapy along with some rescue therapies tried in anecdotal reports. We report here a case of life-threatening overdose of amlodipine with shock, refractory to conventional therapies. Salvage therapy with continuous veno-venous hemodiafiltration using charcoal hemoperfusion with prior infusion of intravenous lipid emulsion resulted in a successful outcome. Medknow Publications & Media Pvt Ltd 2014-06 /pmc/articles/PMC4071686/ /pubmed/24987241 http://dx.doi.org/10.4103/0972-5229.133939 Text en Copyright: © Indian Journal of Critical Care Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Garg, Suneel K.
Goyal, Pankaj K.
Kumar, Rahul
Juneja, Deven
Bhasin, Alka
Singh, Omender
Management of life-threatening calcium channel blocker overdose with continuous veno-venous hemodiafiltration with charcoal hemoperfusion
title Management of life-threatening calcium channel blocker overdose with continuous veno-venous hemodiafiltration with charcoal hemoperfusion
title_full Management of life-threatening calcium channel blocker overdose with continuous veno-venous hemodiafiltration with charcoal hemoperfusion
title_fullStr Management of life-threatening calcium channel blocker overdose with continuous veno-venous hemodiafiltration with charcoal hemoperfusion
title_full_unstemmed Management of life-threatening calcium channel blocker overdose with continuous veno-venous hemodiafiltration with charcoal hemoperfusion
title_short Management of life-threatening calcium channel blocker overdose with continuous veno-venous hemodiafiltration with charcoal hemoperfusion
title_sort management of life-threatening calcium channel blocker overdose with continuous veno-venous hemodiafiltration with charcoal hemoperfusion
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071686/
https://www.ncbi.nlm.nih.gov/pubmed/24987241
http://dx.doi.org/10.4103/0972-5229.133939
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