Cargando…

Hesperidin potentiates the neuroprotective effects of diazepam and gabapentin against pentylenetetrazole-induced convulsions in mice: Possible behavioral, biochemical and mitochondrial alterations

AIM: Epilepsy is a chronic neurological disorder with complex pathophysiology. Several evidences suggest a role of oxidative stress and mitochondrial dysfunction in pathophysiology of epilepsy. Hesperidin (Hesp) acts as a powerful anti-oxidant agent against superoxide, singlet oxygen, and hydroxyl r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kumar, Anil, Lalitha, Sree, Mishra, Jitendriya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071709/ https://www.ncbi.nlm.nih.gov/pubmed/24987179 http://dx.doi.org/10.4103/0253-7613.132180

Ejemplares similares

Hesperidin Interacts With CREB-BDNF Signaling Pathway to Suppress Pentylenetetrazole-Induced Convulsions in Zebrafish
por: Sharma, Pallavi, et al.
Publicado: (2021)

PT603. The contribution of resveratrol to the antiepileptic effects of diazepam and gabapentin
por: Kaygısız, B, et al.
Publicado: (2016)

Study of Rectal Diazepam in Prevention of Simple Febrile Convulsions Recurrence
por: Taghdiri, M M, et al.
Publicado: (2011)

Enhanced sensitivity of laforin- and malin-deficient mice to the convulsant agent pentylenetetrazole
por: García-Cabrero, Ana M., et al.
Publicado: (2014)

Embryonic Exposure to Domoic Acid Increases the Susceptibility of Zebrafish Larvae to the Chemical Convulsant Pentylenetetrazole
por: Tiedeken, Jessica A., et al.
Publicado: (2007)

Hesperidin Ameliorates Immobilization-Stress-Induced Behavioral and Biochemical Alterations and Mitochondrial Dysfunction in Mice by Modulating Nitrergic Pathway
por: Viswanatha, G. L., et al.
Publicado: (2012)

Altered excitatory and inhibitory neocortical circuitry leads to increased convulsive severity after pentylenetetrazol injection in an animal model of schizencephaly, but not of microgyria
por: dos Santos Heringer, Luiza, et al.
Publicado: (2022)

Behavioral and Molecular Responses to Exogenous Cannabinoids During Pentylenetetrazol-Induced Convulsions in Male and Female Rats
por: Zirotti Rosenberg, Antonella, et al.
Publicado: (2022)

Resveratrol is Neuroprotective and Improves Cognition in Pentylenetetrazole-kindling Model of Epilepsy in Rats
por: Meng, X. J., et al.
Publicado: (2014)

Anticonvulsant and Neuroprotective Activities of Phragmanthera austroarabica Extract in Pentylenetetrazole-Kindled Mice
por: Aldawsari, Hibah M., et al.
Publicado: (2017)

Neuroprotective effects of the fractions of Ocimum basilicum in seizures induced by pentylenetetrazole in mice
por: Mansouri, Somaieh, et al.
Publicado: (2022)

Phenotypic modulation of pentylenetetrazole-induced convulsive behaviors in C. elegans carrying a mutation associated with Alzheimer’s disease
por: Vaji, Madeline A., et al.
Publicado: (2020)

Biochemical and toxicological effect of diazepam in stress-induced cardiac dysfunctions
por: Al-Abbasi, Fahad A., et al.
Publicado: (2020)

Hesperidin as a Neuroprotective Agent: A Review of Animal and Clinical Evidence
por: Hajialyani, Marziyeh, et al.
Publicado: (2019)

Neuroprotective effects of Pinus eldarica in a mouse model of pentylenetetrazole-induced seizures
por: Mansouri, Somaieh, et al.
Publicado: (2021)

Anti-convulsant action and amelioration of oxidative stress by Glycyrrhiza glabra root extract in pentylenetetrazole- induced seizure in albino rats
por: Chowdhury, Bimalendu, et al.
Publicado: (2013)

Effect of Duvelisib, a Selective PI3K Inhibitor on Seizure Activity in Pentylenetetrazole-Induced Convulsions Animal Model
por: Abdolrahmani, Mahnaz, et al.
Publicado: (2023)

Anxiety-like behaviour is attenuated by gabapentin, morphine and diazepam in a rodent model of HIV anti-retroviral-associated neuropathic pain
por: Wallace, Victoria C.J., et al.
Publicado: (2008)

Comparative study on the efficacy and safety of low-dose sodium valproate vs. diazepam in the prevention and treatment of pediatric febrile convulsion
por: He, Wei
Publicado: (2020)

Neuroprotective Effects of the Ethanolic Leaf Extract of Crassocephalum crepidioides (Asteracaeae) on Diazepam-Induced Amnesia in Mice
por: Galba Jean, Beppe, et al.
Publicado: (2022)

Hesperidin associated with continuous and interval swimming improved biochemical and oxidative biomarkers in rats
por: de Oliveira, David Michel, et al.
Publicado: (2013)

Headache and neck pain: Gabapentin as a possible treatment
por: Moretti, Rita, et al.
Publicado: (2000)

Reproductive toxicology. Diazepam.
Publicado: (1997)

Investigating Cardiac Morphological Alterations in a Pentylenetetrazol-Kindling Model of Epilepsy
por: Akyuz, Enes, et al.
Publicado: (2020)

Effect of Diazepam on Severity of Acute Pancreatitis: Possible Involvement of Peripheral Benzodiazepine Receptors
por: Abed, Alireza, et al.
Publicado: (2013)

Diazepam ameliorates altered proinflammatory and cardiac markers in stress exposed rats
por: Al-Abbasi, Fahad A.
Publicado: (2021)

Sinomenine exerts anticonvulsant profile and neuroprotective activity in pentylenetetrazole kindled rats: involvement of inhibition of NLRP1 inflammasome
por: Gao, Bo, et al.
Publicado: (2018)

Bioavailability and safety of diazepam intranasal solution compared to oral and rectal diazepam in healthy volunteers
por: Hogan, R. Edward, et al.
Publicado: (2020)

New Sustainable Process for Hesperidin Isolation and Anti-Ageing Effects of Hesperidin Nanocrystals
por: Stanisic, Danijela, et al.
Publicado: (2020)

Alteration of Extracellular Matrix Molecules and Perineuronal Nets in the Hippocampus of Pentylenetetrazol-Kindled Mice
por: Ueno, Hiroshi, et al.
Publicado: (2019)

The Neuroprotective Propensity of Organic Extracts of Acacia stenophylla Bark and Their Effectiveness Against Scopolamine-/Diazepam-Induced Amnesia in Mice
por: Shah, Dawood, et al.
Publicado: (2022)

Ameliorative effect of diazepam against ethanol-induced mitochondrial disruption in brains of the mice
por: Ghasempouri, Seyed Khosro, et al.
Publicado: (2023)

Levetiracetam versus fosphenytoin as a second-line treatment after diazepam for adult convulsive status epilepticus: a multicentre non-inferiority randomised control trial
por: Nakamura, Kensuke, et al.
Publicado: (2023)

Neuroprotective Effect of Fisetin Through Suppression of IL-1R/TLR Axis and Apoptosis in Pentylenetetrazole-Induced Kindling in Mice
por: Khatoon, Saima, et al.
Publicado: (2021)

Attenuated iron stress and oxidative stress may participate in anti-seizure and neuroprotective roles of xenon in pentylenetetrazole-induced epileptogenesis
por: Zhang, Mengdi, et al.
Publicado: (2022)

Effect of Hesperidin on Cardiovascular Disease Risk Factors: The Role of Intestinal Microbiota on Hesperidin Bioavailability
por: Mas-Capdevila, Anna, et al.
Publicado: (2020)

Diazepam Accelerates GABA(A)R Synaptic Exchange and Alters Intracellular Trafficking
por: Lorenz-Guertin, Joshua M., et al.
Publicado: (2019)

The neuroprotective effect of hesperidin in NMDA-induced retinal injury acts by suppressing oxidative stress and excessive calpain activation
por: Maekawa, Shigeto, et al.
Publicado: (2017)

“Protective Premedication”: A Comparative Study of Acetaminophen, Gabapentin and Combination of Acetaminophen with Gabapentin for Post-Operative Analgesia
por: Syal, Kartik, et al.
Publicado: (2010)

A Retrospective Chart Review Examining Gabapentin’s Potential Neuroprotective Effects in Peripheral Nerve Blocks
por: Shuster, David M., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_tfmpivbfquc6ldkt8rbv0ojlqh