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Blast crisis Ph+ chronic myeloid leukemia with NUP98/HOXA13 up-regulating MSI2

BACKGROUND: Musashi2(Msi2)-Numb pathway de-regulation is a molecular mechanism underlying the transition of chronic phase Ph + CML to deadly blast crisis, particularly in cases with a NUP98/HOXA9 fusion from a t(7;11)(p15;p15). This study provides new insights on the mechanisms cooperating in drivin...

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Detalles Bibliográficos
Autores principales:	Di Giacomo, Danika, Pierini, Valentina, Barba, Gianluca, Ceccarelli, Veronica, Vecchini, Alba, Mecucci, Cristina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071805/ https://www.ncbi.nlm.nih.gov/pubmed/24971156 http://dx.doi.org/10.1186/1755-8166-7-42

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