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Increased Frequency of Circulating Follicular Helper T Cells in Children with Hand, Foot, and Mouth Disease Caused by Enterovirus 71 Infection

Enterovirus 71 (EV71) is a major causative agent of hand, foot, and mouth disease (HFMD) in children. The role of T follicular helper (TFH) cells in EV71-infected children remains unclear in regulating humoral immunity. The frequency of circulating ICOS(high)/PD-1(high)CXCR5(+)CD4(+) TFH cells in th...

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Detalles Bibliográficos
Autores principales: Wu, Jianping, Cui, David, Yang, Xianzhi, Lou, Jianzhou, Lin, Jie, Ye, Xianfei, Qin, Zhimei, Huang, Li, Zhao, Dejian, Huo, Zhaoxia, Xie, Guoliang, Zheng, Shufa, Yu, Fei, Lu, Liwei, Chen, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071862/
https://www.ncbi.nlm.nih.gov/pubmed/25013818
http://dx.doi.org/10.1155/2014/651872